TopoFlow documentation

Submission tutorial

Prepare one protein sequence, configure ensemble sampling, and track the generated result.

1

Prepare one protein sequence

TopoFlow accepts either pasted sequence text or one FASTA file. Do not provide both in the same submission.

>my_protein
MGRIFLDHIGGTRLFSCANCDTILTNRSELISTRFTGATGRAFLFNKVVNLQY...

Only the 20 standard amino-acid codes are supported. Multi-record FASTA files are rejected.

2

Choose the ensemble size

Set Number of conformations to an integer from 1 to 100. The default is 10.

3

Add job information

The job name is optional. A valid email address is required for submission and completion notifications.

4

Submit and save the UUID

After the server accepts the job, the page displays a unique UUID. Save it because it identifies the task and its result directory.

Result page format: userResult/{UUID}/index.html
5

Open and download the result

The initial result page shows a waiting state. After processing finishes, the same page provides the completed ensemble and archive.

Result archive: topoflow_results.tar.gz